Delo Home
BCF Home




Mamot
Marcoil
WebMarcoil
Madap




Publications (Pubmed)




SIB group

Homepage of Dr. Mauro Delorenzi

"The combination of molecular investigations, technology and mathematical modelling is a key for further progress in the bio-medical area"


Head Bioinformatics Core Facility (BCF)
NCCR molecular oncology program at ISREC

E-mail:  
Mauro.Delorenzi@isrec.ch
Phone: +41-21 692 4097 & +41-21 692 5857


Address 1:
c/o Swiss Institute Bioinformatics (SIB)
Quartier Sorge, Bâtiment Génopode, Office Room 2021
CH-1015 Lausanne, Switzerland
Phone: (group) +41-21 692 40(91-98)
Fax: +41-21 692 4055
Directions: Local Map and Ways


Address 2:
ISREC (Swiss Institute of Experimental Cancer Research)
Boveresses 155, Office Room D208
CH-1006 Epalinges, Switzerland
Phone: (group) +41-21 692 5857
(secretary: Anne-Marie Rodel) +41-21 692 5939
Fax: +41-21 652 6933
Directions: Local Map and Ways


In March 2002, I joined the Swiss Institute of Experimental Cancer Research in Lausanne (ISREC). Here I am coordinating the activities of the Bioinformatics Core Facility (BCF), devoted mainly to the analysis of Microarray Data. The group is a member of the Swiss Institute of Bioinformatics (SIB).

Currently our main activity is linked to the NCCR molecular oncology program at ISREC (see links at the top and on the left) and to other collaborations, mainly in the area of cancer research.

1999-2002 I was in Terry Speed's group at the Walter and Eliza Hall Institute (Melbourne). I was working in the Sequence Analysis of proteins and nucleic acids. In collaboration wit the groups of Louis Schofield, Brendan Crabb and Alan Cowman we have identified a number of 'interesting target genes' in the genome of Plasmodium falciparum (GPI pathway, new members of the families MSP and RBP/NBP). For the data-mining of Plasmodium falciparum I have used a number of C programs developed for the purpose.
One of the tools we developed is an HMM-based (HMM: hidden Markov model) predictor of coiled-coil domains from primary sequence, Marcoil. It is available as a UNIX C program and also through a web interface (WebMarcoil).
Mamot is a program for easy access to using simple HMMs in teaching and research projects.

Please send comments on web pages to bcf@isb-sib.ch