Madap

The program MADAP was written to serve for automatic annotation of experimental count data on the location of the 5' end of mRNA molecules. The aim is to identify candidates for bona-fide transcription start sites (TSS). The idea was to reproduce the work of a human annotator and to objectivize the choice of putative TSS locations as peaks in a cluster of data "sufficiently" supported by the data. A description of the method can be found here madap.pdf . A web-interface to the program is available at web-madap .